The ointment of psoriasis - what is the ointment more effective for the treatment of psoriasis?

Persons living with a diagnosis of psoriasis", not by hearsay know that, as much, depends on the correct selection of the medicines. It is a disease that does not forgive errors in the treatment and neglect to their health. An important role in the fight against the symptoms of psoriasis play competent picked up outside and prompt therapy and treatment. A key principle in the choice of the scheme of treatment, especially in the early stages of development of psoriasis, is the principle of "do no harm" — made the treatment should not harm the health of the skin, causing the appearance of undesirable effects such as atrophy of the skin or of a withdrawal syndrome. Since the main goal of therapy is to prolong the periods of rest and the health of the skin without sudden and painful of recurrence and exacerbations.

the ointment of psoriasis

Hormonal ointment of the psoriasis: we try to heal or kill?

Common of a group of external means for the treatment of psoriasis are ointments special hormones. These substances have the property of inhibiting the activity of the immune system, reduce inflammation. Therefore, if the exacerbations of psoriasis steroids are prescribed in a systematic way — in the form of pills or injections. However, this approach poses serious side effects: the therapy changes the hormonal state of the body, and the elimination of medications can cause abnormalities in the functioning endocrine and cardiovascular systems.

Topical steroids (external hormonal of the tool), in part, lacking the hazardous properties of the system of drug-based hormones: the effect is manifested only at the site of application. The advantage is the rapidity of the action, as of a few minutes after the application, patients notice decreased itching, and in the next few days, it significantly reduces the redness in the area of psoriatic platelets, stops their growth and scaling.

However, unfortunately, the side effects are topical steroids — and no less serious: because of the reduced immunity at the site of application skin tapers and fade strong, you run the risk of the accession of secondary infection. It is, without doubt, complicates the treatment. The most serious consequence of the application of topical steroids is the development of addiction. As a result of other media (themselves topical steroids) no longer help, leading ordinary, sometimes stronger than the recurrences after drug withdrawal. That is why the sale of topical steroids in europe and the united states without a prescription is prohibited. The independent and the indiscriminate use of these media, refer to the category of powerful, is inadmissible.

It is important to know! Addison's disease is a condition that develops as a result of the prolonged medications corticosteroids. In response to the hormone therapy, adrenal glands stop regardless of to produce cortisol and other steroids, which is manifested by symptoms such as muscle weakness, loss of weight and appetite, decreased blood pressure, dehydration, increased heart rate, and the constant feeling of anxiety. In addison's disease, doctors are not always able to restore the function of the adrenal glands, therefore, patients for life is prescribed as hormonal therapy.

The majority of the media on the basis of topical steroids is cheap and is sold without a prescription, so that cases of abuse of this type of treatment of psoriasis are often found. In the meantime, dermatologists do not recommend the use of steroids with large (more than 20% of the surface of the skin) places the defeat, as well as to apply these tools in the sensitive areas of the body — face, neck, folds of the skin and place a diaper rash. It is desirable at all to give up the idea of apply hormonal ointments and creams without prescription: it is able to reduce the effects of a treatment, cause health risks and lead to a severe attack of exacerbation of psoriasis.

Often hormonal creams and ointments were prepared on the basis of the following substances:

  • betamethasone;
  • hydrocortisone;
  • mometasone;
  • methylprednisolone;
  • triamcinolone;

Traditional non-hormonal ointment for the treatment of psoriasis: the worst and the best?

Taking into account the severe side effects hormone creams and ointments, many patients prefer to treat psoriasis with the assistance of the least "aggressive" of the drugs. Some of them are part of the heritage of the traditional medicine and the most traditional recipes of skin treatment popular in the past.

The traditional advantages of treatment with no hormones psoriasis you must take your comparison with the means of safety, inexpensive, and the absence of serious side effects. The disadvantages is different (often lower) level of efficiency and, in some cases allergic reactions, which develop in patients in components or the other.

the signs of psoriasis
  • Naftalan, Ichthyol, dermatological ointment, base of tar — have anti-inflammatory properties and antiseptic action. However, some of them may not apply when an advanced stage of psoriasis and in large parts of the defeat, while others (for example, tar ointment) have a certain effect, so that it is not recommended to combine with phototherapy. In addition, the long-term use of these funds, increases the likelihood of development of skin cancer. Traditional ointment also have an intense odor and can stain clothing, so that they are not very easy to use.
  • Special of the substance have anti-inflammatory and antimicrobial action, cause, increased flaking of the dead skin cells, which accelerates the process of healing psoriatic platelets. Among the possible side effects, the risk of inflammatory reactions, burning sensation and pigmentation healthy environment of the skin (discoloration of the skin heals and the hair a brown color).
  • Herbal (ointments and creams made of aloe vera, inula salicina, celandine, sage, and other herbs) have anti-inflammatory properties and healing actions that are detrimental to the development of infections of the skin. They are auxiliary means in the treatment of psoriasis, complementing the effect of the primary treatment.
  • The hydration of the tool (schools of creams and oils, cosmetics) are also auxiliary in the treatment of psoriasis, and they help combat the dryness and feeling of tightness of the skin. They are used in combination with drugs to enhance the effect of the therapy performed.

Non-hormonal ointments, and creams, with a marked therapeutic: has been clinically proven

It is worth noting the group of non-hormonal medicines, the efficiency of the local treatment of psoriasis has been confirmed in clinical trials. Unlike the ointments and creams of the previous group, the mechanism of action of these drugs is carefully studied. Have an indisputable advantage over the media in connection with the most high profile of safety. However, and in the treatment of these means, you should strictly follow the instructions of use and to know about possible contraindications.

  • Pimecrolimus has high anti-inflammatory activity. However, you should know that, in the case of bacterial or fungal lesions of the skin the use of tools based on the pimecrolimus is recommended only after the healing of the infection. When uncontrolled use of pimecrolimus can call the local office of the immunosuppression of the skin (the removal of immunity, local), which increases the risk of the accession of secondary infection in areas of the skin. Therefore, in the united states, for example, pimecrolimus is only recommended as a drug of second line treatment, that is to say, only in the absence of the effects of other therapies. Pimecrolimus is denied to the application of children under the age of two years.
  • Calcipotriol is a synthetic analogue of vitamin D3. Its action is based on the increase in the level of calcium in the cells of the skin, which normalizes the speed of division and contributes to the reabsorption psoriatic platelets. Because of calcipotriol is hormonal means (that after a series of biochemical reactions is converted into an active hormonal metabolite calcium exchange), there are a number of restrictions on its use. In particular, calcipotriol does not apply to defeat more than 30% of the surface of the skin due to the risk of hypercalcemia. This last can cause heart rate disturbances, and muscle cramps. There are also advised to apply calcipotriol in the sensitive areas of the skin (face, neck, folds). The tools are based on this, the active substance have an age limit. Calcipotriol also it is not suitable as a support tool in the case of a method of phototherapy treatment, since under the action of uv rays causes photosensitization and leads to the development of the burn of the skin.
  • Pyrithione zinc. At the expense of proven efficacy and safety in the treatment, medicines for the treatment of psoriasis on the basis of this, the active substance can be attributed to the category of funds "the golden mean". Zinc is a organic and natural medicine for the treatment of diseases of the skin. Its concentration in an epithelial human is approximately 20% of the total content in the body, while the deficit of this precious metal accompanied by a variety of skin lesions and the impairment of the healing of the wounds. Medications active zinc (pyrithione zinc) have a range of specific features (anti-inflammatory, antibacterial, antifungal), to help reduce the itching in the skin, contributing to the preparation of ceramides (lipids) in the skin, which leads to the recovery of their barrier function. The tool of pyrithione zinc, activated the so-called apoptosis (natural programmed death) pathologically modified cells of the skin and the cells of the inflammation, therefore, the activation of the natural renewal of skin cells, reducing scaling and eliminating psoriatic of the platelet. Studies have shown that zinc is comparable with the means of efficiency and a good safety profile, since it is practically not absorbed with the surface of the skin, is not irritating and hurts the action.

Ointment or cream?

Many of the above medications are available both in the form of ointment, and cream form. How to choose the most appropriate way?

  • The ointment are more dense and fatty texture that allows the medication to have a lot of time being on the surface of the skin, especially if you put it under the bandage.
  • The cream has a soft texture, easy to apply and absorbed faster, thanks to which you can apply, leaving the skin open, not using the bandages, and without fear of soiling the clothes or hands. As a general rule, the cream has a pleasant smell, which is also important in the daily drawing.
  • Unlike ointment, cream, to a lesser extent, annoyed by the action, therefore, is most suitable for your application on the face, flexural surfaces of the joints, the areas with high sensitivity. Also the ointment is not suitable for application in crying and affected areas of the skin with liquid detachable. The cream in this sense, is more universal.
  • Traditionally, the ointment of psoriasis have been analyzed, however, this imbalance is levelled a little by little, in the market there are more and more new pharmaceutical dosage forms in the form of creams, gels and sprays, easy to use and especially suitable for application in areas inaccessible (for example, in hairy part of the head).
the treatment of psoriasis

Looking for the balance between price and quality

We will try to collect the information received in the form of a table:

The group of the drug

The active substance

The action

Potential limitations and side effects

Hormonal creams and ointments

Betamethasone

Have anti-inflammatory, antiallergic (including antipruritic) and decongestant action. Hydrocortisone-a, methylprednisolone, and other media also have a certain action (overwhelming local immunity of the skin).

1. We do not recommend the use of long duration (over 5 days) and often. 2. Can lead to the development of local complications:

  • the discoloration and the violation of the processes of change in the skin;
  • the withdrawal syndrome;
  • immunosuppressive action may cause the accession of secondary infection of the skin.
  • Contraindicated:
  • for the application in areas with sensitive skin (face, neck, folds);
  • for large areas of the lesion (more than 30% of the skin).

Mometasone

Hydrocortisone

Glucocorticoids tool

Methylprednisolone

Triamcinolone

Non-hormonal traditional media

  • The oil
  • The sulfur
  • Ichthyol
  • The fat lubricacin
  • The tar

Have anti-inflammatory properties and antiseptic action.

  • They have quite a low yield and do not act on bacterial-fungal agents (of the accession of secondary infection of the skin).
  • Are not suitable for use (it is applied several times a day, often under the bandage, require very long treatment regimens, stain clothing and smell unpleasant).
  • Can cause irritation and dryness of the skin, as well as allergic reactions.

The substance that causes active flaking of the dead skin cells from the surface of the skin:

  • dithranol
  • the sulfur and salicylic acid

Cause, increased flaking of the dead skin cells, have anti-inflammatory and antimicrobial action.

Can cause inflammatory reactions, burning sensation and pigmentation healthy environment of the skin (discoloration of the skin heals and the hair a brown color).

Medications are not hormonal

Pimecrolimus

It has anti-inflammatory activity.

  • It is not recommended to use in case of bacterial or fungal lesions of the skin.
  • You can call the immunosuppression of the skin (decreased immunity).
  • It is contraindicated in children under two years of age.

Calcipotriol

It is a synthetic analogue of vitamin D3, contributes to the resorption of psoriatic platelets.

  • Not recommended:
  • apply to defeat more than 30% of the surface of the skin due to the risk of hypercalcemia;
  • apply on sensitive areas of skin (face, neck, the folds, the skin of the head);
  • combined with the method of phototherapy in relation to the risk of receiving a burn of the skin.
  • Is contraindicated for patients under the age of six years.

Pyrithione zinc

Whom the action is complex:

  • anti-inflammatory;
  • antipruritic;
  • the protection of the accession of the infection;
  • activating the natural renewal of skin cells to solve psoriatic platelets;
  • the recovery of the barrier function of the skin.
  • It has a high safety profile.
  • Has No limitations of duration of the application and of the square of the application.
  • Has No side effects (unless you are hypersensitive).
  • Licensed for use in children with a year.

Psoriasis is a chronic disease, so each patient is important to find the best medicine that combines a high efficiency and a minimum of side effects (and advisable for the right price). And remember: before you begin the application of any tool, read the instructions, all the possible contraindications and side effects, as well as, be sure to consult with your doctor. This will help to achieve the best possible result without impairment of health.

the ointment against psoriasis

Early detection and the treatment of psoriasis is a key factor of success. Remember that the sooner you start to heal psoriasis, the less likely it is that you will never have to resort to "heavy artillery" — hormonal contraceptives.

03.10.2018